Study on antioxidant activity of Jujube seed oil

Abstract

Jujube seed oil is pressed by Ziziphi Spinosae Semen，and widely cultivated in China with healthful. Here, we focused on illustrating the components and antioxidant activity of Jujube seed oil. The pressed oil was analyzed by GC-MS. The in vitro antioxidant activity was tested by free radical scavenging. The in vivo antioxidant activity was tested by using Saccharomyces cerevisiae model. The results of GC-MS showed that alkenes (e.g., d-limonene and α-farnesene) were the richest components of jujube seed oil. The experiments of in vitro and in vivo suggested that jujube seed oil possessed good antioxidant capacity. Treatment with Jujube seed oil counteracted oxidative stress-induced by lipid peroxidation and intracellular oxidation in Saccharomyces cerevisiae. Furthermore, experiments performed on missing strains of redox molecules showed that jujube seed oil-induced prevention against lipid peroxidation might be related to catalase encoded by cytosolic catalase T ctt1 gene. Taken together, our current data highlighted the antioxidant capacity of jujube seed oil. Interestingly the Ctt1 activity is vital in the mechanism associated with lipid peroxidation prevention of jujube seed oil.